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Deficiency of vitamin B12 can impair the remethylation of homocysteine in which homocysteine cannot be converted to the amino acid methionine thus accumulating cellular folate as 5-methyl THF

Some claim CJC 1295 with DAC has an advantage over CJC 1295 (without DAC) given it does not have a limited duration of action

Minerva etal Fewer adults had low or transitional vitamin B12 status

Hitting the same spot repeatedly creates scar tissue and chronic irritation

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Not all post-operative numbness requires urgent attention, but certain features should prompt prompt contact with a GP or bariatric team