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For example, the modification (s) in an FX polypeptide are in FXa having a light chain having an amino acid sequence corresponding to amino acid residues 1-139 of SEQ ID NO: 134 and a chain heavy that has an amino acid sequence corresponding to amino acids 195-448 of SEQ ID NO: 134 or one of its variants having catalytic activity and having at least 65%, 70%, 75%, 80%, 85 %, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99% or more of sequence identity with an FXa having a light chain having a sequence of amino acids corresponding to amino acid residues 1-139 of SEQ ID NO: 134 and a heavy chain having an amino acid sequence corresponding to amino acids 195-448 of SEQ ID NO: 134, or to a catalytically active moiety of the same

The use of OPEP devices has demonstrated improvements in phlegm symptoms [12]

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Other Ingredients: Purified water, natural orange and pineapple flavors, stevia leaf extract (steviol glycosides), potassium sorbate

Key proteins involved in iron absorption, transport, storage, and regulation of iron balance are also potential targets for intervention