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As in familial neurodegenerative disorders such as HD, mutations in ubiquitously expressed genes or disease-risk polymorphism in genes highly expressed in astrocytes may also contribute to dysfunctional astrocytes and, consequently adverse neurological outcomes (Lin et al., 2018)

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[Google Scholar] Rijntjes M (2019) Knowing your beans in Parkinsons disease: a critical assessment of current knowledge about different beans and their compounds in the treatment of parkinsons disease and in animal models

Betaine was also able to correct insulin signaling by activating insulin receptor substrate 1 (IRS1) by increasing tyrosine phosphorylation and other signaling mechanisms that regulate gluconeogenesis and glycogen synthesis [28]

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Cancer Res 65 : 14791488 Ma PC, Kijima T, Maulik G, Fox EA, Sattler M, Griffin JD, Johnson BE, Salgia R (2003a) c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions