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Another study in murine models noted a dose-dependent neuroprotective effect of ketone bodies on RGC survival against neurotoxic conditions, suggesting a mechanism of action against neurotoxic metabolites and their downstream effects (Thaler et al., 2010)

By contrast, the subpopulation of astrocytes expressing low levels of Gfap and enriched in genes involved in neural plasticity was reduced in the peri-infarct cortex, but only in mice treated with physiological saline 383

N., Alrawi, R

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27 Researchers have also discovered and proposed three major treatment strategies for age-related diseases, which encompass compound and genetic-engineering-based strategies: senolytics, senomorphics and senoreverse (Fig