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[ 2 ] A decrease in both mitochondrial and cellular levels of glutathione has been associated with a number of chronic conditions , including immune diseases, cardiovascular diseases, neurodegenerative conditions, such as Alzheimer's and Parkinson's, as well as pulmonary diseases such as asthma

The 5-LOX inhibitor, zileuton, is however, approved for treating asthma which could be repurposed as TB HDT and tested to elucidate whether modulation of this pathway improves TB treatment outcomes

Many of the genes encoding ICE-like proteases, henceforth referred to as caspases, were isolated by molecular cloning

Pediatr Res (1999) 46:76771

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Traditional Uses of Medicinal Plants Among the Rural Communities of Churu District in the Thar Desert, India