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Rare cases of allergic contact dermatitis have been described with prolonged copper exposure, so persistent or worsening inflammation should prompt discontinuation and medical evaluation

Celastrol alleviates gamma irradiation-induced damage by modulating diverse inflammatory mediators

In MASLD, elevated CCL2 levels exacerbate liver inflammation by enhancing monocyte and macrophage infiltration [196]

These effects were induced by inhibiting Gata2 expression while enhancing PU.1 levels [47]

Consistently, CYP2E1-induced oxidative stress is modulated by the CYP2E1 inhibitors such as diallyl sulphide (DAS) and phenethyl isothiocyanate (PIC) in both in vivo and in vitro conditions [80, 16]