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259 S-Adenosyl-L-Methionine (SAMe) Reported dosage : 400800 mg per day S-adenosyl-L-methionine (SAMe) is an amino acid metabolite and a crucial methyl donor that is necessary for many biochemical processes, including hormone and neurotransmitter synthesis

Mechanistically, stimulation with either LPS or agonistic CD40 antibody significantly increased expression of Acsl3 and Acsl4 in WT but not SCAP-deficient B cells (109)

Freedman D, Gruchow H, Anderson A, Rimm A, Barboriak JJ

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Mol Cancer Ther 8(9):2509-2516, 2009