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H (400 MHz, CDCl 3 ): 7.97 (1 H, t, J = 5.4 Hz, NH), 7.877.76 (3 H, m, ArH), 7.767.66 (12 H, m, ArH), 3.67 (2 H, s, SCH 2 ), 3.413.25 (2 H, m, PCH 2 ), 3.22 (2 H, apparent q, J = 5.7 Hz, NCH 2 ), 1.771.69 (2 H, m, CH 2 ), 1.671.58 (2 H, m, CH 2 ), 1.581.49 (2 H, m, CH 2 )

Visual indicators include color change (from blue to green, brown, or cloudy), visible particles or precipitation, and unusual film or residue

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Regulation of cholesterol and fatty acid synthesis

Figure created by CEAN group Pedro Carrera Bastos Post How to assess Vitamin B2 Status

A corresponding role for ferroptosis in human ASCVD is also supported by a genetic analysis of human coronary artery plaques which demonstrated a significant positive association between ferroptosis-related gene expression and ASCVD status 80,81