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Furthermore, a recent study demonstrated that oxaliplatin inhibited prolyl hydroxylase, an enzyme that hydroxylates proline in the N-terminal ankyrin repeat of TRPA1, which leads to the enhanced sensitivity of TRPA1 (Miyake et al., 2016)

Additionally, the paper explores the role of gut microbiota dysbiosis in inducing ferroptosis, offering new insights into the gut-ferroptosis-vascular axis as a potential therapeutic target for critically ill patients

In: Tierney LM, McPhee SJ, Papadakis MA, eds

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