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Research over the past 50 years has consistently demonstrated that byproducts released from smoking tobacco products, such as cigarettes, cause permanent cellular and molecular alterations, which lead to cancer (180)(181)(182)

It doesn't directly modulate hormones

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Handling, Reconstitution, & Storage Protocols To maintain the sensitive peptide bonds and prevent premature molecular degradation during your laboratory trials, you must follow these standard storage parameters: Temperature Control and Lyophilized Storage Keep the dry, sealed vials at a consistent temperature of -20C for long-term archival conservation up to 24 months

Itching tends to be absent or mild