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(2) DL, Diluted ad libitum diet where animals were provided with ad libitum access to a low-energy diet diluted with indigestible cellulose, which reduced caloric intake by ~30% and (3) CR, animals in which calories were restricted by 30%, and animals were fed once per day during the start of the light period

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Utilizing sophisticated analytical methods, like liquid chromatography-mass spectrometry (LC-MS), has proven instrumental in dissecting bacterial metabolites and unraveling their functional roles

Qu SY, Li XY, Heng X, Qi YY, Ge PY, Ni SJ, Yao ZY, Guo R, Yang NY, Cao Y, Zhang QC, Zhu HX (2021) Analysis of antidepressant activity of Huang-lian Jie-du decoction through network pharmacology and metabolomics