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Its upregulation in the TOX (+) condition may reflect enhanced activation and mobilization of these innate immune cells in response to ximelagatran-induced stress, supporting its relevance in the early events of DILI pathogenesis

Wetenschappelijke studies richten zich onder andere op de interactie met groeifactor-gerelateerde signaalroutes, extracellulaire matrixremodellering, fibroblastactiviteit, collageengerelateerde processen en de regulatie van celmigratie binnen gecontroleerde onderzoeksmodellen

Maternal diabetes-mediated RORA suppression contributes to gastrointestinal symptoms in autism-like mouse offspring