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The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries

Some common signs of B12 deficiency include: Low energy or fatigue (even after a good nights sleep) Brain fog or memory lapses Mood swings, anxiety, or irritability Numbness or tingling in hands and feet Poor immune function Sound familiar

Initiation and progression of PD is dependent upon cellular events, including failures in the protein degradation machinery, oxidative stress, mitochondrial dysfunction, defects in mitochondrial autophagy (mitophagy) and the continuous accumulation of -synuclein, driven through cell to cell interactions between glial cells and neurons that ultimately lead to apoptosis [7,10,18]