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Hydroxyl and carbonate radicals Hydroxyl radical is one of the most reactive radicals occurring in biological systems and causes damage to all important biomolecules involving DNA, proteins, and membranes (Valko et al

An eGFR just below 60 typically indicates the presence of early-stage CKD and is also associated with a significantly increased risk of cardiovascular and any-cause mortality, kidney failure, acute kidney injury, or the progression of CKD

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models

Thiol-reduced glutathione (GSH) synthesis GSH is made available in cells through 3 processes, summarized in Figure 1

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The total radical-trapping antioxidant parameter (TRAP) assay quantifies the capacity of antioxidants to delay fluorescence decay in a probe (such as R-phycoerythrin or dichlorofluorescein) under controlled peroxidative conditions initiated by AAPH-generated ROO