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Biomedicine & Pharmacotherapy, 57, 145-155

For instance, global transcriptomic analyses have revealed reduced expression of several antioxidant enzymes in ovulated oocytes recovered from aged mice and human donors 4, 30, 31

PLoS One 8 , e76057, (2013)

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Potential users should be aware that while preclinical safety appears excellent, the absence of extensive human clinical trials means unknown risks may exist