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Gastrointestinal disorders and surgeries Some GI-related conditions and surgeries may affect B12 absorption: Crohns disease: A chronic inflammatory disease, Crohns affects the small and large intestine particularly the distal ileum, which is where B12 is absorbed

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Curcumin, baicalin, and resveratrol downregulate MMP-9 via MAPK and NF-B inhibition, reducing endothelial permeability and leukocyte trafficking

Thus, hepatitis B treatment goals are categorized into functional and complete cure, whereby functional cure is defined as HBsAg clearance or levels below 0.05 IU/mL, undetectable HBV DNA or levels below 10 IU/mL, with or without HBsAg seroconversion[6], the complete cure is considered as the total eradication of HBV DNA, including cccDNA and integrated HBV DNA, from the liver and serum[7]