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Caspase-3 is often described as an executioner enzyme in the programmed cell death pathway, because once it becomes activated and cleaved, it appears to orchestrate the dismantling of the cell through the proteolytic breakdown of essential structural and regulatory proteins

Mitochondrial dysfunction is involved in the pathogenesis of numerous cardiovascular diseases, including ischemic cardiomyopathy, HF, and diabetic cardiomyopathy

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Experimental data suggest that organisms with high GLUT4 expression may expend more energy, while those with low GLUT4 expression conserve more calories

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Certain tirzepatide compound formulations can cause more injection site irritation than others