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Description

APE1 is a 37 kDa ubiquitous multifunctional protein involved in the regulation of multiple transcription factors, including NF-B, STAT3, AP-1, hypoxia-inducible factor-1 (HIF-1), and tumor protein 53 (p53

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Ramos-Casals M, Soto MJ, Cuadrado MJ et al (2009) Rituximab in systemic lupus erythematosus: a systematic review of off-label use in 188 cases

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Induction of eosinophil apoptosis by hydrogen peroxide promotes the resolution of allergic inflammation

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Instead, it may affect other tissues and organs, including small nerve fibres and the brain

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Interestingly, increasing glutathione (a derivate of the glutamine metabolism) has shown to favour a M1 response in M [18]

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Methods: Clinical trial NCT04073368 was simulated by several software packages

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