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Although xCT expression is confined to the plasma membrane in normal tissues (36,39), it is upregulated in certain types of cancer, such as colorectal cancer, malignant glioma and non-small cell lung cancer, which increases cystine uptake (4042)

DauletbaevNFischerPAulbachBGrossJKuscheWThyroff-FriesingerUet al

doi: 10.1002/jgm.1334 179 ArrigoniPRuprechtJCChasseDADGlassKAAndressBGuilakFet al

Treatment improved foot position, motor recovery, early jumping, reduced nociception deficits, and accelerated total antioxidant capacity healing [136]

Gently swirl the vial with circular motions (NEVER shake!) for 30 to 60 seconds until all the powder has dissolved

(Pececnik et al., 2025) These are genuinely interesting mechanistic observations