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The importance of this antioxidant pathway is illustrated in Nrf2 knockout mice in which lung neutrophil inflammation and pulmonary emphysema were evident as early as 8 weeks after cigarette smoke exposure, whereas wild-type mice showed no lung changes at 16 weeks

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doi: 10.1016/j.jalz.2018.02.005 Summary Keywords epigenetic regulation, DNA methylation, neurological diseases, ICF syndrome, multiple sclerosis, Rett syndrome, Alzheimers disease, Parkinsons disease Citation Li L, Chen R, Zhang H, Li J, Huang H, Weng J, Tan H, Guo T, Wang M and Xie J (2024) The epigenetic modification of DNA methylation in neurological diseases

Other sources of diagnostic error are premature menopause, obesity, and other endocrine causes of amenorrhea

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