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Other side effects, along with remedies, are explored further in this article

(Folate deficiency disrupts normal DNA synthesis and methylation, which interferes with cell division and development, especially in rapidly dividing embryos.) Megaloblastic anemia, which can lead to symptoms like fatigue, weakness, and difficulty concentrating Elevated homocysteine, even when B12 levels are normal

the increase in fetal hemoglobin retards gelation and sickling of RBCs

doi: 10.1016/j.gene.2018.11.014 221 LiuLZuoYXuYZhangZLiYPangJ