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Enforced expression of SLC27A5 contributed to the upregulation of genes promoting lipid peroxidation and dysregulation of iron homeostasis (Figs

Incapsula incident ID: 350000780008405650-13216335947240335

This mutation results in the production of a mutant protein with an elongated polyglutamine region, leading to the accumulation of protein aggregates in neurons, particularly in the basal ganglia and cerebral cortex

L.KeithB.LiuQ.et al (2009)

Aging (Albany NY) 2 (8), 471474

These include hydrophobic attraction of nonpolar side chains in contact regions of the subunits, electrostatic interactions between ionic groups of opposite charge: hydrogen bonds between polar groups