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The AcM enzyme used in this study is same as the one previously described [28] and marketed under the trade name of Balancius TM (dsm-firmenich animal nutrition and health, Wurmisweg, 576, 4303, Kaiseraugst, Switzerland).The gene coding for this AcM is from the fungus Acremonium alcalophilum (strain 114.92), and its activity is expressed in MUR units LSU(F)

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The iron-sulfur cluster in the L-serine dehydratase TdcG from Escherichia coli is required for enzyme activity

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Conversely, miR-23a-3p targets cul3, a principal regulator of Nrf2 ubiquitination and degradation, thereby further increasing the activity of Nrf2

Vitamin C contributes to the reduction of tiredness and fatigue