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It has been found in cellular, animal, and clinical trials that EPA can resist skin aging, be anti-inflammatory, and promote wound healing, not only used as a dietary supplement but also topically used on the skin (6365), which inferred that the effect of KO on improving skin health may be related to the high ratio of EPA

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A pilot study on intraarticular knee pain found that 7 of 12 patients reported improvement lasting six or more months

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There was no consistent pattern of gross pathological lesions in these animals