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Both are short peptides studied in neuro and circadian-adjacent research, but they differ chemically

Evolving role of thiopurines in inflammatory bowel disease in the era of biologics and new small molecules

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LAMP2 dysregulation disrupts lysosomal homeostasis, and also impairs the activity of Cathepsin D (CTSD), a key protease for autophagosomal cargo degradation (116,117)

Of course, it's easiest to reduce calorie intake and increase activity, but it's harder to make gains in endurance and stamina this way