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As we proposed in section III.G.7.c.(2).(d) of the CY 2025 PFS proposed rule (89 FR 61907), if the reopened PY becomes a BY for a subsequent agreement period, CMS would adjust the historical benchmark to be used for any PY in that subsequent agreement period that has not yet been reconciled

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AuNPs can either encapsulate chemotherapeutic agents or be employed to deliver RNA molecules such as targeting siRNA or message mRNA [17]

Dosing and Mechanism of Action The time interval for maximal benefits varies throughout the transgender population, with an average of 18-24 months of therapy to achieve desired results

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