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DIAGNOSIS OF INCIDENT DEMENTIA AND ALZHEIMER DISEASE Members of the dementia cohort have been monitored for the development of stroke and dementia since their inclusion in the cohort.1 Participants were routinely administered a screening Mini-Mental State Examination at each biennial examination.16 Persons who scored below education-based cutoffs or who experienced a decline of 3 or more points on the Mini-Mental State Examination from the most recent previous examination were called back for a neurological and neuropsychological examination

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The blue color is a useful spectroscopic and visual handle for monitoring copper complexation, for assessing the integrity of the complex in solution, and for distinguishing the copper-bound form from the apo-peptide (which is colorless or pale)

However, they are not without risks, and potential side effects should be considered