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However, excessive/insufficient mitophagy, inhibition of mitochondrial biogenesis, and an overall reduction in protein synthesis can lead to mitochondrial dysfunction, causing insufficient ATP production or an increased burden of ROS, which in turn cannot meet the cellular demands, ultimately leading to energy deprivation and cell death

Ferroptosis has been implicated in the occurrence and treatment response of various types of cancer, and targeting ferroptosis has emerged as a promising strategy for cancer therapy

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Well, if spermidine is going to be considered an anti-aging vitamin, where is that vitamin found

Med Sci Sports Exerc 38 (1): 7280

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