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10.1016/S1875-5364(24)60603-5 118 WangY.WuS.LiQ.SunH.WangH

The findings further illustrate the diversified modes of metformin in NAFLD treatment with direct effects on the liver and indirect actions via extrahepatic pathways

Collectively, our findings show that acetyl-L-carnitine attenuated LPS-induced neuroinflammation by targeting TLR4/NFB pathway, autophagy and oxidative stress

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Moreover, albeit large-scale studies and trials support the anti-cancer potential of PDE5i, the association between PDE5 inhibition and tumor microenvironment, universally acknowledged to be critical in driving tumor growth/invasion/metastasis, and response to therapies, is still lacking

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