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Notably, the voltage-dependent anion channel (VDAC) in the mitochondrial outer membrane, also known as the mitochondrial pore, acts as a gatekeeper for the entry and exit of mitochondrial metabolites and is a convergence point for its binding to various ligands and proteins to mediate various cell survival and cell death signals [47]

10.7759/cureus.49082 19 GuoR.WangB.LiuD.HuangY.LuY

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Consequently, restoring redox equilibrium represents a promising avenue for overcoming therapy resistance and advancing targeted anticancer strategies that exploit the inherent redox vulnerabilities of malignant cells [33]

Dispose of expired or compromised vials per local medical-waste regulations