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42 demonstrated that in mice, hepatocyte zonation only became defined after Day 56 post-birth

Neuwelt EA, Lawrence MS, Blank NK

The 15-residue synthetic fragment was numbered 157 within the original research nomenclature used by the discovering group, producing the BPC-157 designation that subsequently became the standard name in published literature

R-spondin 3 acts as a Wnt enhancer and is vital to injury repair by inducing more differentiated Lgr4 + cells to regain Wnt production, and thus generate new crypts 29,30

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