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Li M, Konteatis Z, Nagaraja N et al (2022) Leveraging structure-based drug design to identify next-generation MAT2A inhibitors, including brain-penetrant and peripherally efficacious leads

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NCT06602193)

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Biochimica et Biophysica Acta (BBA)-Bioenergetics

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Moreover, certain cancer cells enter a state of quiescent growth during the treatment process, known as drug-tolerant persister (DTP), which allows them to evade the apoptosis induced by chemotherapy and targeted therapy [130]

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