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Looking forward, enhancing the bioavailability and targeted delivery of polyphenols could open new avenues in drug development for metabolic disorders, dermatological applications, and the formation of functional foods aimed at improving physical performance and overall well-being

This relationship is broken by oxidative or electrophilic stressors, which allows Nrf2 to nuclear translocate and attach to antioxidant response molecules (AREs)

BMC Musculoskelet Disord

Metabolic pathways as potential targets have two distinct advantages: firstly, they are common to various cancers and secondly, some cancer cells have been shown to be dependent on certain metabolic pathways that these targets serve

2003 Oct;56(5):270-4

Below, we summarize four major categories of polyphenolsflavonoids, phenolic acids, stilbenes, and lignanshighlighting representative compounds and their potential roles in PD prevention or therapy