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Similarly, another study demonstrated nephrotoxicity in colitis mice treated with green tea extract containing 35% EGCG, evidenced by increased serum creatinine levels (a nephropathy biomarker), and elevated expression of antioxidant enzymes (HO-1 and NQO1) and HSP 90 (238)

CrossRefPubMedDirect Link Caimi, G., C

Low levels of glutathione and often concurrently high levels of inflammation are found in many chronic disease states

Zudem enthalten vor allem industriell verarbeitete Nahrungsmittel ihrerseits Radikale und Chemikalien, fr deren Neutralisierung das in der Nahrung vorhandene GSH vom Organismus benutzt werden muss

These findings suggest that SPAE mitigates DEX-induced hepatic stress by modulating upstream regulators of antioxidant and metabolic pathways, namely, Keap1 and AMPK, as shown in Figure 8

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