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Supplementation with vitamin E has been shown to attenuate BBB leakage and protect against cognitive impairment following I/R injury, suggesting its potential as a protective agent for the BBB (Freeman and Keller, 2012

The variation in the erythrocyte GSH system without nuclear capacity to restore homeostasis may be an early biomarker of chronic oxidative stress that could be a first step in the development of cardiometabolic complications

Rab-related proteins in cancer

Neuropharmacology 177 , 108247 (2020)

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Thus, these studies highlight the importance of sustained stress paradigms for modeling the progressive nature of neurodegenerative diseases