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SOD enzymes convert superoxide radicals to hydrogen peroxide (less reactive) for further detoxification by catalase and glutathione peroxidase

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Retrograde Mitochondrial-Nuclear Signaling One interesting feature of MOTS-c biology is that MOTS-c seems to travel to the nucleus of cells under conditions of stress and alter the expression of nuclear genes that control antioxidant defences as well as metabolic programs

*Correspondence: Wolfgang Stremmel, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers