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doi:10.1177/1060028016645826

Fatigue: L-Carnitine supplementation may help to reduce fatigue and improve exercise performance in people with chronic fatigue syndrome and other conditions

Defective or insufficient mitochondrial function at the cellular level is thought to impact whole-body metabolic homeostasis

It serves as a coenzyme in the mitochondrial oxidative phosphorylation pathway, shuttling electrons between complexes I/II and complex III of the electron transport chain to generate adenosine triphosphate (ATP)

Seconda fase della reazione Nella seconda reazione, gli acidi grassi attivati che sono destinati all'ossidazione mitocondriale vengono trasportati nella matrice da una proteina carrier, ma prima l'acil-CoA deve essere transitoriamente attaccato al gruppo ossidrile di carnitina per formare l'acil-carnitina grasso

Coenzyme Q10 supplementation In ageing and disease