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Neelakantan et al., 2018) and hepatocytes (Song et al., 2020)

Can animal doses be extrapolated to cellular experiments

doi:10.1161/jaha.123.031676

Aegypti (requires a blood meal for egg production) versus Ae

Research progress Support The animal experiments have achieved remarkable results: In the obese mouse model, after daily subcutaneous injection of AOD 9604 (250 g/kg) for 8 weeks, the body weight of the mice decreased by 12%, the subcutaneous fat mass decreased by 25%, and the weight of epididymal adipose tissue significantly decreased, confirming its effectiveness in fat reduction

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