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extract alleviate cataract development by regulating the mitochondrial apoptotic pathway of the lens epithelial cells

GSH is the most abundant intracellular antioxidant synthesized using glycine, cysteine, and glutamine, and a lack of GSH could contribute to oxidative stress and the development of obesity-associated complications

Therefore, some studies suggest that FAs undergo passive diffusion across membranes owing to their limited water solubility [33,34,35]

Notably, the -mangostin-loaded formulation resulted in a greater extent of protein corona formation, likely due to changes in nanoparticle physicochemical properties, which in turn increased RAB5A and CD36 adsorption and significantly improved brain distribution and microglial uptake

However, leukocyte vitamin C concentration does not accurately reflect vitamin C in several tissues and may specifically underestimate vitamin C uptake into skeletal muscle (26)

Statins, widely prescribed inhibitors of HMG-CoA reductase (HMGCR) 11 , the rate-limiting enzyme of the pathway (Figure 1), have demonstrated anti-proliferative effects in multiple cancer models 810