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The interaction between DUSP3-NPM was already demonstrated in cells exposed to genotoxic stress (Panico and Forti, 2013), and here we show in vitro that DUSP3 has very high binding affinity to NPM, even stronger than the DUSP3-ERK1 interaction, a classic substrate of this phosphatase in in vitro and in vivo studies (Supplementary Figure 8)

Liu B, Jiang M, Zhu D et al (2022) Metal-organic frameworks functionalized with nucleic acids and amino acids for structure- and function-specific applications: a tutorial review

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In aged CBA mice, in vitro treatment with Epithalon (and its pineal precursor epithalamin) enhanced the thymus microenvironment by increasing stromal precursor fibroblasts and thymic serum factor

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