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Glutathione is a powerful antioxidant which protects cells from free radical damage

Ascorbic acid suppresses house dust mite-induced expression of interleukin-8 in human respiratory epithelial cells

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The maintenance in the active state of pyruvate dehydrogenase complex that oxidizes pyruvate to acetyl CoA stimulates oxidative phosphorylation

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There is also increasing evidence that deregulation of GSH synthesis contributes to the pathogenesis of diseases such as diabetes mellitus, pulmonary and hepatic fibrosis, alcoholic liver disease, cholestatic liver injury, endotoxemia, and drug-resistant tumors cells [10]