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Moreover, alcoholics may experience reduced intestinal absorption of vitamin B 12 (2), and individuals with acquired immunodeficiency syndrome (AIDS) appear to be at increased risk of deficiency, possibly related to a failure of the IF-B 12 receptor to take up the IF-B 12 complex (3)

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doi: 10.1210/jc.2018-00070

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That said, although side effects from vitamin B12 supplementation are very rare, it can possibly occur with B12 injections, but not with oral supplements

Our experience shows that this is the best initial state for extended 5-Amino-1MQ storage