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Sedentary life impairs self-reparative processes in the brain: the role of serum insulin-like growth factor-I

This subsequently activates the key effector caspases caspase-3/7 and cascades to activate caspase-2/6/8/10, ultimately executing apoptosis [41]

[DOI] [PubMed] [Google Scholar] 18.Kim DS, Park SH, Kwon SB, Youn SW, Park KC

doi: 10.3389/fphar.2022.895193 187 YanR.ZhangY.LiY.XiaL.GuoY.ZhouQ

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139 In contrast, YAP1-mediated TFRC and ACSL4 expression, as well as WWTR1-mediated epithelial membrane protein 1 (EMP1) and angiopoietin-like 4 (ANGPTL4) expression, promotes ferroptosis in human renal cell carcinoma or ovarian cancer cells by increasing iron accumulation and lipid peroxidation