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303 , E1036E1052 (2012)

Please refer to this study for potential markers and prospective therapies

Perhaps more importantly, the data provided by Schultz et al

however, the underlying mechanisms are unclear

doi: 10.1111/jfbc.13612 111 NakagawaY

These nanoparticles can be designed to release drugs in reaction to particular chemical alterations in hypoxic conditions, such as elevated acidity or the presence of enzymes