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J Nutr Biochem

Am J Prev Med 47: 166-174

Li S., Lin X., and Duan L., Harnessing the Power of Natural Alkaloids: The Emergent Role in Epilepsy Therapy, Frontiers in Pharmacology 15, no

Using changes in N -methyl-D-aspartate (NMDA) receptor EPSC decay time as a measure of synaptic spillover, the authors demonstrated an EAAT2-dependent increase in decay time in heroin-treated rats compared to controls

These findings indicate that m imbalance not only disrupts oxidative phosphorylation but also alters substrate flux, linking mitochondrial bioenergetics to systemic metabolic signatures

Paul SE, Hatoum AS, Fine JD, Johnson EC, Hansen I, Karcher NR, et al