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Interestingly, when we optimized the cell sorting procedure by using free settling to replace magnetic separation, the EGFP positive cell percentage could be elevated from 20% to over 95% in K-562 cells for both GST-EGFP-GPI DAF and GST-EGFP-GPI BY55 (Figure 3C)

For example, selenium-deficient animals and human cell lines exhibit reduced transcription of selenoproteins such as GPX1 , DIO s, SELENOI , and SELENOW 55,56,57

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We hypothesize that IL-6-STAT3 signaling is a promising therapeutic target for the cytokine storm in COVID-19, because IL-6 is a major STAT3 stimulator, particularly during inflammation