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In addition to standard care, the HABIT groups received nebulization treatment through a nebulizer (KST-Y, China) every 6 h for 7 consecutive days starting on the second day of admission

TJs are adhesions between endothelial cells that are composed of multiple transmembrane proteins, including claudin, occludin, junctional adhesion molecule, and zonula occludens-1 (ZO-1)

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Notes on Viral Titer Units: TU/mL (Transducing Units/mL): Used for lentiviral vectors, represrmting the concentration of functional viral particles capable of transducing target cells and expressing the transgene