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Based on this model, it has also been shown that NKT cells, which secrete both IL-4 and IFN, are critical to the development of liver injury [112]

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p53 inhibitor UBX0101-induced was found to be a potent senolytic in vivo , reduced oxidative stress, promoted partial cartilage repair and suppressed inflammation

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These proteins cleave NAD + into NAM, ADPR, or cyclic ADP-ribose (cADPR)

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By directly binding to SLC7A11, recombinant human autophagy effector protein (BECN1) inhibits the activity of system x c , promotes GSH consumption and lipid peroxidation, and induces ferroptosis in cancer cells [137]

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[103] reported the opposite findings, suggesting that Bmal1 negatively influences the pluripotency of MSCs

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MiR-30d inhibits cardiomyocytes autophagy promoting ferroptosis after myocardial infarction

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