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10.1016/j.clinthera.2005.11.011 97 JhaP.JacobB.GajalakshmiV.GuptaP

Combination of omega 3 and coenzyme Q10 exerts neuroprotective potential against hypercholesterolemia-induced Alzheimers-like disease in rats

2), S335S356

GCH1-mediated defense mechanism GTP cyclohydrolase-1 (GCH1) is the rate-limiting enzyme in the biosynthesis of tetrahydrobiopterin (BH4), a critical cofactor necessary for various biochemical processes, including the synthesis of monoamine neurotransmitters and the regulation of nitric oxide levels (178,179)