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pylori and the worsening of motor symptoms in PD patients (71)

doi: 10.1016/j.aquaculture.2010.09.003

Since MLN4924 only affects cullin-dependent RING E3 ubiquitin ligases (Duda et al, 2008), but not RNF4, this data confirmed that CCW28-3 induced RNF4-independent degradation via a different but so far unidentified cullin-dependent RING E3 ligase

and de Villartay, J-P

The NOAEL for developmental toxicity is 10 mg/m 3

Additional information Peer review information Nature Communications thanks Alessandro Giuffr and the other, anonymous, reviewer(s) for their contribution to the peer review of this work